Interstate 76 is an unusual interstate: it consists of two non-contiguous segments. The western segment runs 188 miles from Denver, Colorado northeast to Big Springs, Nebraska, where it terminates at I-80. The eastern segment runs 437 miles from Akron, Ohio across the Pennsylvania Turnpike to the New Jersey Shore at Camden — including the famous Breezewood gap with I-70.
For freight, the eastern segment (which carries the Pennsylvania Turnpike) is the dominant corridor and one of the most-tolled interstate corridors in the eastern US. The western segment is a connector between Denver and the I-80 corridor, used heavily by Front Range freight bound for Chicago and the Great Lakes.
Geographically the western segment crosses the high plains of eastern Colorado and western Nebraska. The eastern segment threads the Allegheny Mountains across Pennsylvania — the original mountain segment includes the famed Allegheny Mountain and Tuscarora Mountain tunnels — before descending into the Susquehanna Valley and the Philadelphia metro.
- Two non-contiguous segments — western (CO-NE) and eastern (OH-PA-NJ)
- Eastern segment is the Pennsylvania Turnpike (heavily tolled)
- Includes 4 of the 7 Pennsylvania Turnpike mountain tunnels
- Crosses the Allegheny Front at over 2,400 ft
- Western segment ends at I-80 in Big Springs, NE
- Concurrent with I-70 from Pittsburgh to Breezewood
- Eastern terminus at Camden, NJ on the Walt Whitman Bridge approach